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Benefits of using the LentiVector® platform
Oxford Biomedica offers unrivalled lentiviral vector expertise, drawn from broad clinical and commercial experience. Our proprietary LentiVector® platform offers a range of benefits, including:
- fully compliant analytical methods, recognised by regulatory bodies around the world
- next-generation manufacturing technologies that drive down cost per dose
- an established serum-free suspension bioreactor process – Process B
- a best-in-class perfusion bioreactor process – Process C offering superior yield and quality
- access to unique chemical and mRNA enhancers
- automated product-specific experiment designs
- optimised cell lines for a scalable manufacturing process
- expertise with different lentiviral-based vectors (HIV, SIV, EIAV) and using various pseudotypes to target specific cells
- ‘minimal’ 3rd generation vector systems with key safety features
What makes the LentiVector® platform unique?
340+
GMP batches successfully released in the past 9 years
Track record
- 25+ years of manufacturing experience (GMP manufacturing since 2014)
- Validated commercial platform
- Availability of Drug Masterfile with the FDA
19E+12 TU
Vector product generated for therapeutic gene at 200L scale
Performance
- Recognised leading platform by multiple emerging biotechs and pharma companies
9-fold
Titre improvement achieved for a LV-CAR product with OXB technologies
Innovation
- Technologies and process upgrades to improve vector titre, quality, potency, safety, consistency of manufacture and scalability
12 months
Fastest timeline achieved from client onboarding to released GMP batch
Fast to GMP
- Rapid entry to clinical trials without the need for tech transfer and process changes
40+
Number of countries with a commercially approved product using our Lentivirus vector
Tech transfer
- Possibility to tech transfer the LentiVector® platform to your facilities
8,000+
Number of patients treated using our Lentiviral vector
Client focus
- Trusted by broad range of customers, from emerging biotech and large pharmaceutical companies
- Strong focus on project management and communication
Access to unique technologies
Our flexible licensing structure gives you access to unique technologies, along with the support you need to develop and deliver groundbreaking new lentiviral-based products.
Achieve your objectives more easily using our advanced and reliable technologies: