Resources library

5 Questions with… Ceri Schofield

How can Quality accelerate programme success while reducing risk? In this edition of 5 Questions with..., Ceri Schofield, VP and Head of Quality at OXB, shares her perspective on the increasingly strategic role of Quality in viral vector development.

An Engineered Helper Plasmid Generates Differential E4orf6 and L4-22/33K Gene Expression Increasing AAV Vector Production

Discover how engineered helper plasmids can increase AAV yields by up to fivefold while preserving vector quality, offering a scalable approach to more efficient AAV manufacturing.

Podcast: Building quality at scale – How viral vector CDMOs stay inspection ready

Melanie Kearney, SVP and Global Head of Quality explores how connecting R&D and manufacturing earlier can prevent delays and unnecessary complexity, why audits don’t have to be something to “get through” but can actually become a competitive advantage, and how clear communication and continuous improvement help turn change into opportunity.

Structural Analysis of Recombinant AAV Vector Genomes at Single-Molecule Resolution

This paper presents a long-read analysis pipeline for accurately classifying recombinant AAV genome heterogeneity to improve vector characterization and design.

The use of ShakeReactors™ for optimisation, characterisation, and predictive modelling in lentiviral vector bioproduction

In collaboration with @atSpiro, our new white paper explores how ShakeReactors™ can help bridge the gap between early-stage experimentation and manufacturing-scale performance.

The TetraVecta™ System: Optimisation & Exemplification of OXB’s Next Generation Lentiviral Vector