Resources library
Welcome to our resource library. We invite you to explore and view our extensive resources and information.
5 Questions with… Melanie Kearney
Quality is about more than compliance. It's about building confidence at every stage of development. In this edition of 5 Questions with..., Dr. Melanie Kearney, SVP, Global Head of Quality at OXB, explores why Quality should be embedded from the very beginning of a cell and gene therapy programme.
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Structural Analysis of Recombinant AAV Vector Genomes at Single-Molecule Resolution
This paper presents a long-read analysis pipeline for accurately classifying recombinant AAV genome heterogeneity to improve vector characterization and design.
View PDF >5 Questions with… Ceri Schofield
How can Quality accelerate programme success while reducing risk? In this edition of 5 Questions with..., Ceri Schofield, VP and Head of Quality at OXB, shares her perspective on the increasingly strategic role of Quality in viral vector development.
View PDF >The use of ShakeReactors™ for optimisation, characterisation, and predictive modelling in lentiviral vector bioproduction
In collaboration with @atSpiro, our new white paper explores how ShakeReactors™ can help bridge the gap between early-stage experimentation and manufacturing-scale performance.
View PDF >The TetraVecta™ System: Optimisation & Exemplification of OXB’s Next Generation Lentiviral Vector
View PDF >Enhancing Titres of Therapeutic Viral Vectors using the Transgene Repression in Vector Production TRiP System
This paper describes using a TRiP system to temporarily repress transgene expression during production, boosting viral vector titers for therapeutic use.
View PDF >Gene Therapy for Parkinson’s Disease: Preclinical Evaluation of Optimally Configured TH:CH1 Fusion for Maximal Dopamine Synthesis
This research evaluates a lentiviral vector encoding an optimized TH-CH1 fusion enzyme, showing improved dopamine synthesis for Parkinson’s therapy.
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