Knowledge Centre

View and download our resources

Journal Papers

Time‐Dependent Sorption Behavior of Lentiviral Vectors During Anion‐Exchange Chromatography

Lentiviral Vector Determinants of Anion‐Exchange Chromatography Elution Heterogeneity

Membrane Adsorber Design for Lentiviral Vector Recovery

Transduction of Photoreceptors With Equine Infectious Anemia Virus Lentiviral Vectors: Safety and Biodistribution of StarGen for Stargardt Disease

Transduction Patterns of Pseudotyped Lentiviral Vectors in the Nervous System

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White Papers and Case Studies

Case Study: Tech transfer across borders: transferring lentivirus manufacture from the UK to FranceSeptember 2025

Comparison of 2 Emulsion-Based Digital PCR Systems: ddPCR from BioRad versus dPCR from Stilla, for Reliable Determination of AAV Genome Titre

Significant Improvements In Total Lentiviral Titer And Quality Seen By Implementing Process C, A Perfusion-Based System

Time‐Dependent Sorption Behavior of Lentiviral Vectors During Anion‐Exchange Chromatography

Improving Manufacturing Conditions: Use of DOEs for Optimal LV Production

Achieving rAAV Bioreactor Titer of 1E15 vgL With Novel Plasmid Transient Transfection Platform

Advancing Gene Therapy Development with a Multi Type AAV Affinity Resin

Enhancing Titres of Therapeutic Viral Vectors using the Transgene Repression in Vector Production TRiP System

Innovative Platforms For Improved Viral Vector Development And Scale-Up

Novel Dual-Plasmid Transfection System Improves Titer And Product Quality In AAV Manufacturing

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Webinars and Videos

Webinar: How to Optimize AAV Potency through Effective Formulation Strategies

Presentation: Accelerate Time to Clinic- A Platform and Analytics Approach

Webinar: Accelerating Viral Vector Manufacturing: The Use of Automation from Early Stage to QC Release

Podcast: Achieving Better AAV Productivity

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Posters & Presentations

What’s Upstream of Downstream Matters: Utilising High-Efficiency Secreted Nuclease (SecNuc™ Enzyme) and Transgene Repression (TRiP System™) to Improve rAAV Production

Development and Scale Up of Next Generation Lentiviral Vector Batch Process Demonstrating Increased Productivity and Enhanced Purity

The TetraVecta™ System: Optimisation & Exemplification of OXB’s Next Generation Lentiviral Vector

Increasing AAV Productivity Upstream Process Optimization for a Robust, Plug-and-Play Platform

Accelerate Time to Clinic: A Platform and Analytics Approach

Diving Deeper: Using a SYBR Gold Capsid Ejection Assay as an Orthogonal Method of Measuring Potency and VP1 Deamidation in AAV9 Drug Product Samples

Enhancing Upstream Processes for High-Yield, High-Quality AAV Vector Production Using a Novel In-House Cell Line

The Impact of Individual Helper Genes on AAV Productivity

Evaluation of Salt-Tolerant Endonucleases for Lentiviral Vector Purification

Enhancing Titers of Therapeutic Lentiviral Vectors using PKC Agonists

The 3 Rs Of Replication-Competent Lentivirus (RCL) Formation Risk: Real, Rare, or Artificial?

Optimising the Production of the 4th Generation Lentiviral Vector (LV) TetraVecta™ System: Towards Plug-and-Play LV Manufacturing

The TetraVecta™ System: A New Tool Kit Enhancing Lentiviral Vector Production and Performance for the Next Generation of Gene Therapies

TetraVecta™ Packaging Cell Lines for LV-CAR Production

Engineering an AAV Viral Vector Production Cell Line SV40 T Antigen Locus Removal in HEK293T via Mad7 Genome Editing

Advanced Nuclease Applications in Lentiviral Vector Bioprocessing for Superior Downstream Recovery and Vector Product Quality

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Articles

Efficient In Vivo Generation of CAR T Cells using a Retargeted Fourth-Generation Lentiviral Vector

Shaping the Future of Medicine Through Cell and Gene Therapy Innovation

Conquering the Complexities of AAV Manufacturing: Advances in Efficiency, Scalability, Compliance

Exploring Viral Clearance for AAV Products: A Study of Detergent Lysis and Chromatography Steps

Knowledge Centre

View and download our resources

Time‐Dependent Sorption Behavior of Lentiviral Vectors During Anion‐Exchange Chromatography

Lentiviral Vector Determinants of Anion‐Exchange Chromatography Elution Heterogeneity

Membrane Adsorber Design for Lentiviral Vector Recovery

Transduction of Photoreceptors With Equine Infectious Anemia Virus Lentiviral Vectors: Safety and Biodistribution of StarGen for Stargardt Disease

Transduction Patterns of Pseudotyped Lentiviral Vectors in the Nervous System

Case Study: Tech transfer across borders: transferring lentivirus manufacture from the UK to FranceSeptember 2025

Comparison of 2 Emulsion-Based Digital PCR Systems: ddPCR from BioRad versus dPCR from Stilla, for Reliable Determination of AAV Genome Titre

Significant Improvements In Total Lentiviral Titer And Quality Seen By Implementing Process C, A Perfusion-Based System

Time‐Dependent Sorption Behavior of Lentiviral Vectors During Anion‐Exchange Chromatography

Improving Manufacturing Conditions: Use of DOEs for Optimal LV Production

Achieving rAAV Bioreactor Titer of 1E15 vgL With Novel Plasmid Transient Transfection Platform

Advancing Gene Therapy Development with a Multi Type AAV Affinity Resin

Enhancing Titres of Therapeutic Viral Vectors using the Transgene Repression in Vector Production TRiP System

Innovative Platforms For Improved Viral Vector Development And Scale-Up

Novel Dual-Plasmid Transfection System Improves Titer And Product Quality In AAV Manufacturing

Webinar: How to Optimize AAV Potency through Effective Formulation Strategies

Presentation: Accelerate Time to Clinic- A Platform and Analytics Approach

Webinar: Accelerating Viral Vector Manufacturing: The Use of Automation from Early Stage to QC Release

Podcast: Achieving Better AAV Productivity

What’s Upstream of Downstream Matters: Utilising High-Efficiency Secreted Nuclease (SecNuc™ Enzyme) and Transgene Repression (TRiP System™) to Improve rAAV Production

Development and Scale Up of Next Generation Lentiviral Vector Batch Process Demonstrating Increased Productivity and Enhanced Purity

The TetraVecta™ System: Optimisation & Exemplification of OXB’s Next Generation Lentiviral Vector

Increasing AAV Productivity Upstream Process Optimization for a Robust, Plug-and-Play Platform

Accelerate Time to Clinic: A Platform and Analytics Approach

Diving Deeper: Using a SYBR Gold Capsid Ejection Assay as an Orthogonal Method of Measuring Potency and VP1 Deamidation in AAV9 Drug Product Samples

Enhancing Upstream Processes for High-Yield, High-Quality AAV Vector Production Using a Novel In-House Cell Line

The Impact of Individual Helper Genes on AAV Productivity

Evaluation of Salt-Tolerant Endonucleases for Lentiviral Vector Purification

Enhancing Titers of Therapeutic Lentiviral Vectors using PKC Agonists

The 3 Rs Of Replication-Competent Lentivirus (RCL) Formation Risk: Real, Rare, or Artificial?

Optimising the Production of the 4th Generation Lentiviral Vector (LV) TetraVecta™ System: Towards Plug-and-Play LV Manufacturing

The TetraVecta™ System: A New Tool Kit Enhancing Lentiviral Vector Production and Performance for the Next Generation of Gene Therapies

TetraVecta™ Packaging Cell Lines for LV-CAR Production

Engineering an AAV Viral Vector Production Cell Line SV40 T Antigen Locus Removal in HEK293T via Mad7 Genome Editing

Advanced Nuclease Applications in Lentiviral Vector Bioprocessing for Superior Downstream Recovery and Vector Product Quality

Efficient In Vivo Generation of CAR T Cells using a Retargeted Fourth-Generation Lentiviral Vector

Shaping the Future of Medicine Through Cell and Gene Therapy Innovation

Conquering the Complexities of AAV Manufacturing: Advances in Efficiency, Scalability, Compliance

Exploring Viral Clearance for AAV Products: A Study of Detergent Lysis and Chromatography Steps

What Does 2025 Hold For Biopharma? Part 1: The State Of The Biopharma Industry

Maintaining Momentum with OXB’s CEO, Dr. Frank Mathias

AAV: inAAVate™ Platform Infographic

AAV: Addressing AAV Manufacturing Challenges

AAV: Novel Dual-Plasmid Transfection System

LV: LentiVector™ Platform

LV: TetraVecta™ System Brochure

LV: Clinical & Commercial Manufacturing of Lentiviral Vectors

LV: LentiStable™ Packaging and Producer Cell Lines

Driving Innovation in Cell and Gene Therapy